HCSGD entry for SMG1

1. General information

Official gene symbolSMG1
Entrez ID23049
Gene full namesmg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Other gene symbols61E3.4 ATX LIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIDA NAS TASbiological_process
GO:0004672Protein kinase activityTASmolecular_function
GO:0004674Protein serine/threonine kinase activityEXP IDA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0006950Response to stressIDAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0018105Peptidyl-serine phosphorylationIDA TASbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0046854Phosphatidylinositol phosphorylationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13599123890.97776897910.74431802871.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.7025339114
GSE28863_A2Up0.2474972891
GSE28863_A3Down-0.5364752648
GSE28863_A4Up0.1477762183
GSE48662Up0.2297904182

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017428MicroarrayFunctional MTI (Weak)18185580
hsa-miR-877-5pMIMAT0004949MIRT037357CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039989CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040595CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044095CLASHFunctional MTI (Weak)23622248
hsa-miR-181a-5pMIMAT0000256MIRT047307CLASHFunctional MTI (Weak)23622248
hsa-miR-106a-5pMIMAT0000103MIRT048317CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048500CLASHFunctional MTI (Weak)23622248
hsa-miR-17-3pMIMAT0000071MIRT050767CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052316CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.