HCSGD entry for FOXE3

1. General information

Official gene symbolFOXE3
Entrez ID2301
Gene full nameforkhead box E3
Other gene symbolsFKHL12 FREAC8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0002089Lens morphogenesis in camera-type eyeIBAbiological_process
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA TASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006590Thyroid hormone generationIBAbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0008134Transcription factor bindingIBAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0030878Thyroid gland developmentIBAbiological_process
GO:0031069Hair follicle morphogenesisIBAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048468Cell developmentIEAbiological_process
GO:0048562Embryonic organ morphogenesisIBAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051090Regulation of sequence-specific DNA binding transcription factor activityIBAbiological_process
GO:0060022Hard palate developmentIBAbiological_process
GO:0060023Soft palate developmentIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52770422860.76172710380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0959200519
GSE13712_SHEARDown-0.0969022764
GSE13712_STATICDown-0.0816568039
GSE19018Up0.0731177701
GSE19899_A1Up0.0495153971
GSE19899_A2Up0.0861146913
PubMed_21979375_A1Up0.4396228765
PubMed_21979375_A2Down-0.1282332580
GSE35957Up0.0196260174
GSE36640Down-0.0121595664
GSE54402Up0.0455292649
GSE9593Down-0.0414566437
GSE43922Up0.1372934456
GSE24585Up0.2371237682
GSE37065Down-0.0470111882
GSE28863_A1Down-0.3003841982
GSE28863_A2Up0.1051678063
GSE28863_A3Up0.4499232976
GSE28863_A4Down-0.0387135059
GSE48662Up0.1147327349

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.