HCSGD entry for PLCH1
1. General information
| Official gene symbol | PLCH1 |
|---|---|
| Entrez ID | 23007 |
| Gene full name | phospholipase C, eta 1 |
| Other gene symbols | PLCL3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004435 | Phosphatidylinositol phospholipase C activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | IDA | biological_process |
| GO:0050429 | Calcium-dependent phospholipase C activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7780979864 | 0.3769454846 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0519081153 |
| GSE13712_SHEAR | Up | 0.0274765290 |
| GSE13712_STATIC | Down | -0.0542288866 |
| GSE19018 | Up | 0.0388025744 |
| GSE19899_A1 | Down | -0.0514946068 |
| GSE19899_A2 | Down | -0.0593156062 |
| PubMed_21979375_A1 | Up | 0.0206643252 |
| PubMed_21979375_A2 | Up | 0.1217434661 |
| GSE35957 | Up | 0.1179919430 |
| GSE36640 | Up | 0.3377869680 |
| GSE54402 | Up | 0.1478678925 |
| GSE9593 | Up | 0.0843119245 |
| GSE43922 | Up | 0.0115638150 |
| GSE24585 | Down | -1.1631517284 |
| GSE37065 | Up | 0.1002663629 |
| GSE28863_A1 | Down | -0.3072591014 |
| GSE28863_A2 | Up | 0.0862565352 |
| GSE28863_A3 | Up | 0.1181808629 |
| GSE28863_A4 | Down | -0.0538986337 |
| GSE48662 | Up | 0.0166405288 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
