HCSGD entry for MAST1
1. General information
| Official gene symbol | MAST1 |
|---|---|
| Entrez ID | 22983 |
| Gene full name | microtubule associated serine/threonine kinase 1 |
| Other gene symbols | SAST SAST170 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA ISS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | ISS | biological_process |
| GO:0007010 | Cytoskeleton organization | ISS | biological_process |
| GO:0035556 | Intracellular signal transduction | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3646618745 | 0.9134475096 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0893828137 |
| GSE13712_SHEAR | Down | -0.0692678453 |
| GSE13712_STATIC | Up | 0.0322744892 |
| GSE19018 | Up | 0.0659938523 |
| GSE19899_A1 | Down | -0.0401329005 |
| GSE19899_A2 | Up | 0.0439471125 |
| PubMed_21979375_A1 | Up | 0.0695765089 |
| PubMed_21979375_A2 | Down | -0.1948662772 |
| GSE35957 | Up | 0.1605636915 |
| GSE36640 | Down | -0.0710491148 |
| GSE54402 | Up | 0.0733209189 |
| GSE9593 | Up | 0.1307899938 |
| GSE43922 | Up | 0.1038529369 |
| GSE24585 | Up | 0.1088077917 |
| GSE37065 | Up | 0.0170481634 |
| GSE28863_A1 | Down | -0.1370776697 |
| GSE28863_A2 | Down | -0.0013143020 |
| GSE28863_A3 | Up | 0.4496830700 |
| GSE28863_A4 | Up | 0.0981494249 |
| GSE48662 | Up | 0.3135152271 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017887 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019332 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
