HCSGD entry for TCF25
1. General information
| Official gene symbol | TCF25 |
|---|---|
| Entrez ID | 22980 |
| Gene full name | transcription factor 25 (basic helix-loop-helix) |
| Other gene symbols | Hulp1 NULP1 PRO2620 hKIAA1049 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007507 | Heart development | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9589305687 | 0.0492225865 | 0.9999902473 | 0.4148535703 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0866749030 |
| GSE13712_SHEAR | Down | -0.5037735656 |
| GSE13712_STATIC | Down | -0.3470269601 |
| GSE19018 | Down | -0.1129475230 |
| GSE19899_A1 | Down | -0.8589217932 |
| GSE19899_A2 | Down | -0.3180371241 |
| PubMed_21979375_A1 | Down | -1.0679000513 |
| PubMed_21979375_A2 | Down | -0.8185895311 |
| GSE35957 | Up | 0.0052701052 |
| GSE36640 | Up | 0.2568112308 |
| GSE54402 | Up | 0.1278493797 |
| GSE9593 | Up | 0.0474556540 |
| GSE43922 | Down | -0.6649789517 |
| GSE24585 | Up | 0.2093087732 |
| GSE37065 | Down | -0.1075896207 |
| GSE28863_A1 | Up | 0.0355938184 |
| GSE28863_A2 | Down | -0.1103834418 |
| GSE28863_A3 | Down | -0.2222252487 |
| GSE28863_A4 | Up | 0.0328896279 |
| GSE48662 | Up | 0.1291270159 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037265 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046271 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050402 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
