HCSGD entry for PAXIP1

1. General information

Official gene symbolPAXIP1
Entrez ID22976
Gene full namePAX interacting (with transcription-activation domain) protein 1
Other gene symbolsCAGF29 PACIP1 PAXIP1L PTIP TNRC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000416Positive regulation of histone H3-K36 methylationISSbiological_process
GO:0001570VasculogenesisIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006310DNA recombinationIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0010212Response to ionizing radiationIDAbiological_process
GO:0016363Nuclear matrixIEAcellular_component
GO:0030330DNA damage response, signal transduction by p53 class mediatorIMPbiological_process
GO:0031398Positive regulation of protein ubiquitinationISSbiological_process
GO:0035066Positive regulation of histone acetylationISSbiological_process
GO:0035097Histone methyltransferase complexIDAcellular_component
GO:0043542Endothelial cell migrationIEAbiological_process
GO:0045830Positive regulation of isotype switchingISSbiological_process
GO:0051568Histone H3-K4 methylationIDAbiological_process
GO:0051571Positive regulation of histone H3-K4 methylationISSbiological_process
GO:0060261Positive regulation of transcription initiation from RNA polymerase II promoterIMP ISSbiological_process
GO:0060612Adipose tissue developmentIEAbiological_process
GO:0060717Chorion developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94165846660.02897654340.99999024730.3229007621

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0985414589
GSE13712_SHEARUp0.0543938672
GSE13712_STATICUp0.0603552452
GSE19018Down-0.6626722001
GSE19899_A1Down-0.4612349533
GSE19899_A2Down-0.2552278807
PubMed_21979375_A1Up0.2459440789
PubMed_21979375_A2Down-0.3332565274
GSE35957Down-0.9199718720
GSE36640Down-1.5472881373
GSE54402Up0.0210681650
GSE9593Down-0.5494254399
GSE43922Up0.0330666500
GSE24585Down-0.1777986872
GSE37065Down-0.2014221843
GSE28863_A1Up0.2436714673
GSE28863_A2Up0.4990217570
GSE28863_A3Up0.0060510792
GSE28863_A4Down-0.0746049409
GSE48662Down-0.5979813386

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-32-5pMIMAT0000090MIRT028345SequencingFunctional MTI (Weak)20371350
hsa-miR-339-5pMIMAT0000764MIRT042768CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.