HCSGD entry for FOXD1
1. General information
| Official gene symbol | FOXD1 |
|---|---|
| Entrez ID | 2297 |
| Gene full name | forkhead box D1 |
| Other gene symbols | FKHL8 FREAC4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007411 | Axon guidance | IEA | biological_process |
| GO:0008301 | DNA binding, bending | IDA | molecular_function |
| GO:0010628 | Positive regulation of gene expression | ISS | biological_process |
| GO:0030513 | Positive regulation of BMP signaling pathway | IEA ISS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0060678 | Dichotomous subdivision of terminal units involved in ureteric bud branching | IEA ISS | biological_process |
| GO:0072076 | Nephrogenic mesenchyme development | IEA | biological_process |
| GO:0072210 | Metanephric nephron development | IEA | biological_process |
| GO:0072213 | Metanephric capsule development | ISS | biological_process |
| GO:0072267 | Metanephric capsule specification | IEA ISS | biological_process |
| GO:0090184 | Positive regulation of kidney development | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8223437863 | 0.0854728392 | 0.9999902473 | 0.5550778682 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4194792259 |
| GSE13712_SHEAR | Up | 0.1327439073 |
| GSE13712_STATIC | Up | 0.0472849425 |
| GSE19018 | Up | 0.5567269393 |
| GSE19899_A1 | Up | 0.1048154603 |
| GSE19899_A2 | Up | 0.2835491804 |
| PubMed_21979375_A1 | Down | -0.6784384228 |
| PubMed_21979375_A2 | Down | -0.2314327412 |
| GSE35957 | Up | 0.1090804874 |
| GSE36640 | Down | -0.5882169009 |
| GSE54402 | Up | 0.1260839063 |
| GSE9593 | Up | 0.0260050037 |
| GSE43922 | Down | -0.0813652713 |
| GSE24585 | Down | -0.0119452811 |
| GSE37065 | Down | -0.3772163446 |
| GSE28863_A1 | Down | -0.3744146580 |
| GSE28863_A2 | Down | -0.0790457349 |
| GSE28863_A3 | Up | 0.0967234279 |
| GSE28863_A4 | Down | -0.2249228227 |
| GSE48662 | Down | -0.2979079639 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT007277 | Luciferase reporter assay | Functional MTI | 23445407 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024787 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
