HCSGD entry for SCMH1
1. General information
| Official gene symbol | SCMH1 |
|---|---|
| Entrez ID | 22955 |
| Gene full name | sex comb on midleg homolog 1 (Drosophila) |
| Other gene symbols | Scml3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0010369 | Chromocenter | IEA | cellular_component |
| GO:0016458 | Gene silencing | ISS | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IC NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9860684510 | 0.0037400023 | 0.9999902473 | 0.1241752837 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1484384637 |
| GSE13712_SHEAR | Down | -0.8333494664 |
| GSE13712_STATIC | Up | 0.0057986819 |
| GSE19018 | Down | -0.0226069468 |
| GSE19899_A1 | Down | -0.5799686306 |
| GSE19899_A2 | Down | -1.5247955287 |
| PubMed_21979375_A1 | Down | -1.0224609103 |
| PubMed_21979375_A2 | Down | -1.2665378712 |
| GSE35957 | Down | -0.7912318300 |
| GSE36640 | Down | -0.5877143946 |
| GSE54402 | Down | -0.2282269694 |
| GSE9593 | Up | 0.0447179750 |
| GSE43922 | Down | -1.2541356272 |
| GSE24585 | Down | -0.0352655217 |
| GSE37065 | Down | -0.3608854855 |
| GSE28863_A1 | Down | -0.0259606829 |
| GSE28863_A2 | Up | 0.1725932918 |
| GSE28863_A3 | Down | -0.4860345528 |
| GSE28863_A4 | Down | -0.2707649321 |
| GSE48662 | Up | 0.3318866937 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-Mercaptoethanol | DB03345 | EXPT02882 | DB03131 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024711 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026128 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-532-3p | MIMAT0004780 | MIRT037923 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047441 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051461 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
