HCSGD entry for FOXF2
1. General information
| Official gene symbol | FOXF2 |
|---|---|
| Entrez ID | 2295 |
| Gene full name | forkhead box F2 |
| Other gene symbols | FKHL6 FREAC-2 FREAC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001837 | Epithelial to mesenchymal transition | NAS | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IC IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0030198 | Extracellular matrix organization | IEA | biological_process |
| GO:0042249 | Establishment of planar polarity of embryonic epithelium | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0048566 | Embryonic digestive tract development | IEA | biological_process |
| GO:0048596 | Embryonic camera-type eye morphogenesis | IEA | biological_process |
| GO:0048806 | Genitalia development | IMP | biological_process |
| GO:0060021 | Palate development | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1388243000 | 0.3772146119 | 0.7493835931 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0796066746 |
| GSE13712_SHEAR | Down | -0.0838951305 |
| GSE13712_STATIC | Down | -0.2844095325 |
| GSE19018 | Down | -0.2625097955 |
| GSE19899_A1 | Up | 0.0423779242 |
| GSE19899_A2 | Up | 0.6498610872 |
| PubMed_21979375_A1 | Down | -0.6767078758 |
| PubMed_21979375_A2 | Up | 1.2884871676 |
| GSE35957 | Down | -0.3603743230 |
| GSE36640 | Up | 1.9486816925 |
| GSE54402 | Up | 0.0995096025 |
| GSE9593 | Down | -0.3741088512 |
| GSE43922 | Up | 0.0909017086 |
| GSE24585 | Up | 0.0047376632 |
| GSE37065 | Up | 0.0662641806 |
| GSE28863_A1 | Up | 0.0510910381 |
| GSE28863_A2 | Up | 0.1685458281 |
| GSE28863_A3 | Up | 0.0201510457 |
| GSE28863_A4 | Down | -0.0619739351 |
| GSE48662 | Down | -0.4587953422 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-182-5p | MIMAT0000259 | MIRT007330 | Luciferase reporter assay | Functional MTI | 23383207 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022115 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028797 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
