HCSGD entry for ELL2
1. General information
| Official gene symbol | ELL2 |
|---|---|
| Entrez ID | 22936 |
| Gene full name | elongation factor, RNA polymerase II, 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | IEA | biological_process |
| GO:0008023 | Transcription elongation factor complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1980919608 | 0.2787195319 | 0.8604134520 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3274941852 |
| GSE13712_SHEAR | Up | 0.8615170843 |
| GSE13712_STATIC | Up | 0.9083997404 |
| GSE19018 | Up | 0.1003645777 |
| GSE19899_A1 | Down | -0.3337615525 |
| GSE19899_A2 | Down | -0.1883695965 |
| PubMed_21979375_A1 | Up | 0.0768947625 |
| PubMed_21979375_A2 | Down | -0.1710563094 |
| GSE35957 | Up | 0.8719466487 |
| GSE36640 | Up | 0.2467991703 |
| GSE54402 | Down | -0.3792345420 |
| GSE9593 | Up | 0.1850297106 |
| GSE43922 | Down | -0.0644271899 |
| GSE24585 | Up | 0.4083253433 |
| GSE37065 | Up | 0.1014994214 |
| GSE28863_A1 | Down | -0.2424000243 |
| GSE28863_A2 | Down | -0.4462328022 |
| GSE28863_A3 | Down | -0.0548425523 |
| GSE28863_A4 | Down | -0.1670767154 |
| GSE48662 | Up | 0.0916001098 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020029 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024649 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026909 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
