HCSGD entry for SEPHS1
1. General information
| Official gene symbol | SEPHS1 |
|---|---|
| Entrez ID | 22929 |
| Gene full name | selenophosphate synthetase 1 |
| Other gene symbols | SELD SPS SPS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004756 | Selenide, water dikinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IDA IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9964276205 | 0.0022188253 | 0.9999902473 | 0.0907090062 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5161221122 |
| GSE13712_SHEAR | Down | -0.5238001170 |
| GSE13712_STATIC | Down | -0.4846677621 |
| GSE19018 | Down | -0.3119073563 |
| GSE19899_A1 | Down | -0.7574311160 |
| GSE19899_A2 | Down | -1.0209183614 |
| PubMed_21979375_A1 | Down | -0.8958245968 |
| PubMed_21979375_A2 | Down | -0.9475751994 |
| GSE35957 | Down | -0.6441846448 |
| GSE36640 | Down | -1.6224754167 |
| GSE54402 | Down | -0.5271509502 |
| GSE9593 | Down | -0.6794902444 |
| GSE43922 | Down | -0.1604672260 |
| GSE24585 | Down | -0.3568404680 |
| GSE37065 | Down | -0.1915641150 |
| GSE28863_A1 | Up | 0.1875915871 |
| GSE28863_A2 | Up | 0.0884718340 |
| GSE28863_A3 | Down | -0.0672639398 |
| GSE28863_A4 | Up | 0.2581507950 |
| GSE48662 | Down | -0.2625832280 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016476 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040065 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041988 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046882 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
