HCSGD entry for SEPHS2
1. General information
| Official gene symbol | SEPHS2 |
|---|---|
| Entrez ID | 22928 |
| Gene full name | selenophosphate synthetase 2 |
| Other gene symbols | SPS2 SPS2b |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004756 | Selenide, water dikinase activity | IEA NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0016260 | Selenocysteine biosynthetic process | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0371270013 | 0.8984573306 | 0.4364015514 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6555751930 |
| GSE13712_SHEAR | Down | -0.1223040154 |
| GSE13712_STATIC | Up | 0.0828760413 |
| GSE19018 | Down | -0.3530945936 |
| GSE19899_A1 | Up | 0.4419611479 |
| GSE19899_A2 | Up | 0.5907846602 |
| PubMed_21979375_A1 | Up | 0.8444337346 |
| PubMed_21979375_A2 | Up | 1.1574029260 |
| GSE35957 | Up | 0.2269091838 |
| GSE36640 | Up | 0.1982872380 |
| GSE54402 | Up | 0.1625221531 |
| GSE9593 | Up | 0.5397161910 |
| GSE43922 | Up | 0.1279289597 |
| GSE24585 | Down | -0.2164897422 |
| GSE37065 | Down | -0.1854273813 |
| GSE28863_A1 | Up | 0.0151633400 |
| GSE28863_A2 | Up | 0.0484952985 |
| GSE28863_A3 | Down | -0.4175446254 |
| GSE28863_A4 | Up | 0.2512187334 |
| GSE48662 | Up | 0.0151368320 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036036 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039955 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041273 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
