HCSGD entry for MAPRE1
1. General information
| Official gene symbol | MAPRE1 |
|---|---|
| Entrez ID | 22919 |
| Gene full name | microtubule-associated protein, RP/EB family, member 1 |
| Other gene symbols | EB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IEA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | TAS | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0030981 | Cortical microtubule cytoskeleton | IDA | cellular_component |
| GO:0031115 | Negative regulation of microtubule polymerization | IDA | biological_process |
| GO:0031253 | Cell projection membrane | IEA | cellular_component |
| GO:0035371 | Microtubule plus-end | IEA | cellular_component |
| GO:0035372 | Protein localization to microtubule | IDA | biological_process |
| GO:0051010 | Microtubule plus-end binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9724744159 | 0.1290838038 | 0.9999902473 | 0.6916968241 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1265827617 |
| GSE13712_SHEAR | Up | 0.0733986448 |
| GSE13712_STATIC | Down | -0.0718136981 |
| GSE19018 | Down | -0.3974291637 |
| GSE19899_A1 | Down | -0.2066697074 |
| GSE19899_A2 | Down | -0.1205718835 |
| PubMed_21979375_A1 | Up | 0.1060008970 |
| PubMed_21979375_A2 | Down | -0.3576658737 |
| GSE35957 | Down | -0.2051582860 |
| GSE36640 | Down | -0.1912256948 |
| GSE54402 | Up | 0.1866031741 |
| GSE9593 | Down | -0.0013635817 |
| GSE43922 | Down | -0.0037675197 |
| GSE24585 | Down | -0.0810876301 |
| GSE37065 | Up | 0.0441216376 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5294143732 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10b-5p | MIMAT0000254 | MIRT007026 | Luciferase reporter assay | Functional MTI | 21562367 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023330 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027584 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037211 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038886 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042656 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049331 | CLASH//Luciferase reporter assay//qRT-PCR | Functional MTI | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
