HCSGD entry for SACM1L
1. General information
| Official gene symbol | SACM1L |
|---|---|
| Entrez ID | 22908 |
| Gene full name | SAC1 suppressor of actin mutations 1-like (yeast) |
| Other gene symbols | SAC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0004438 | Phosphatidylinositol-3-phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | ISS TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016791 | Phosphatase activity | ISS | molecular_function |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0032281 | Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex | IEA | cellular_component |
| GO:0034593 | Phosphatidylinositol bisphosphate phosphatase activity | IEA | molecular_function |
| GO:0042578 | Phosphoric ester hydrolase activity | IEA | molecular_function |
| GO:0043812 | Phosphatidylinositol-4-phosphate phosphatase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5699088446 | 0.2885720413 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1051449492 |
| GSE13712_SHEAR | Up | 0.1480843905 |
| GSE13712_STATIC | Down | -0.0456083993 |
| GSE19018 | Down | -0.1627878733 |
| GSE19899_A1 | Up | 0.0367300749 |
| GSE19899_A2 | Up | 0.1214649915 |
| PubMed_21979375_A1 | Up | 0.1210966004 |
| PubMed_21979375_A2 | Down | -0.0566279667 |
| GSE35957 | Up | 0.2905064105 |
| GSE36640 | Up | 0.3309472380 |
| GSE54402 | Down | -0.2865929500 |
| GSE9593 | Up | 0.1650261960 |
| GSE43922 | Up | 0.0624208544 |
| GSE24585 | Up | 0.0308161762 |
| GSE37065 | Up | 0.2249871379 |
| GSE28863_A1 | Down | -0.1387567471 |
| GSE28863_A2 | Up | 0.1567450740 |
| GSE28863_A3 | Down | -0.8788895306 |
| GSE28863_A4 | Down | -0.1186056568 |
| GSE48662 | Down | -0.7453829425 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT005254 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027375 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029463 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030850 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031704 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042889 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049103 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
