HCSGD entry for DZIP1
1. General information
| Official gene symbol | DZIP1 |
|---|---|
| Entrez ID | 22873 |
| Gene full name | DAZ interacting zinc finger protein 1 |
| Other gene symbols | DZIP DZIPt1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005814 | Centriole | IDA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007281 | Germ cell development | NAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0036064 | Ciliary basal body | IDA | cellular_component |
| GO:0042384 | Cilium assembly | IMP | biological_process |
| GO:0043234 | Protein complex | NAS | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9870470613 | 0.0092014171 | 0.9999902473 | 0.1894334375 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1910301139 |
| GSE13712_SHEAR | Down | -0.0921369229 |
| GSE13712_STATIC | Up | 0.1838299560 |
| GSE19018 | Down | -0.6727847777 |
| GSE19899_A1 | Down | -0.8010495207 |
| GSE19899_A2 | Down | -1.0704922605 |
| PubMed_21979375_A1 | Down | -2.2872436544 |
| PubMed_21979375_A2 | Down | -1.2454193538 |
| GSE35957 | Down | -0.1120471320 |
| GSE36640 | Up | 0.1151946705 |
| GSE54402 | Down | -0.1917069898 |
| GSE9593 | Down | -0.1347566986 |
| GSE43922 | Down | -0.7144893758 |
| GSE24585 | Up | 0.0385295932 |
| GSE37065 | Down | -0.1045211738 |
| GSE28863_A1 | Up | 0.0414755025 |
| GSE28863_A2 | Down | -0.0969245967 |
| GSE28863_A3 | Down | -0.3118053600 |
| GSE28863_A4 | Up | 0.1110530605 |
| GSE48662 | Down | -0.1460508256 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005040 | Microarray | Functional MTI (Weak) | 17699775 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022498 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-99b-3p | MIMAT0004678 | MIRT038523 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051692 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22355768 | Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease |
| 22355768 | An association between a rare, coding, non-synonymous SNP variant in the gene DZIP1 and Parkinson's disease was found, based on an analysis of the existing NGRC genome-wide association study dataset |
| 22355768 | The association of DZIP1 with Parkinson's disease is discussed in the context of a Parkinson's disease stem-cell ageing theory |
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