HCSGD entry for CHSY1
1. General information
| Official gene symbol | CHSY1 |
|---|---|
| Entrez ID | 22856 |
| Gene full name | chondroitin sulfate synthase 1 |
| Other gene symbols | CHSY CSS1 ChSy-1 TPBS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005576 | Extracellular region | IDA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030204 | Chondroitin sulfate metabolic process | TAS | biological_process |
| GO:0030206 | Chondroitin sulfate biosynthetic process | IDA TAS | biological_process |
| GO:0030279 | Negative regulation of ossification | IMP | biological_process |
| GO:0031667 | Response to nutrient levels | IEA | biological_process |
| GO:0032580 | Golgi cisterna membrane | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0047238 | Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | IDA | molecular_function |
| GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9789874359 | 0.0074924281 | 0.9999902473 | 0.1731415277 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0859965742 |
| GSE13712_SHEAR | Down | -0.3281218491 |
| GSE13712_STATIC | Down | -0.3135029277 |
| GSE19018 | Up | 0.0617640176 |
| GSE19899_A1 | Down | -0.7352765916 |
| GSE19899_A2 | Down | -0.6191959149 |
| PubMed_21979375_A1 | Down | -0.7052266812 |
| PubMed_21979375_A2 | Down | -0.7533907404 |
| GSE35957 | Down | -0.1019811899 |
| GSE36640 | Down | -0.5563947092 |
| GSE54402 | Down | -0.3139782243 |
| GSE9593 | Down | -0.4470543229 |
| GSE43922 | Down | -0.2374907613 |
| GSE24585 | Down | -0.1617361950 |
| GSE37065 | Down | -0.0976294855 |
| GSE28863_A1 | Up | 0.0904244046 |
| GSE28863_A2 | Down | -0.0061994336 |
| GSE28863_A3 | Up | 0.6000897637 |
| GSE28863_A4 | Down | -0.0121707836 |
| GSE48662 | Down | -0.4904771895 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002605 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002605 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT002768 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-375 | MIMAT0000728 | MIRT019774 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021396 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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