HCSGD entry for DOLK
1. General information
| Official gene symbol | DOLK |
|---|---|
| Entrez ID | 22845 |
| Gene full name | dolichol kinase |
| Other gene symbols | CDG1M DK DK1 SEC59 TMEM15 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004168 | Dolichol kinase activity | IDA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | TAS | biological_process |
| GO:0006489 | Dolichyl diphosphate biosynthetic process | TAS | biological_process |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0043048 | Dolichyl monophosphate biosynthetic process | IDA | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1454104783 | 0.4373744197 | 0.7643996804 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5465620868 |
| GSE13712_SHEAR | Down | -0.2221575852 |
| GSE13712_STATIC | Down | -0.2747549438 |
| GSE19018 | Down | -0.4515641284 |
| GSE19899_A1 | Down | -0.3589199298 |
| GSE19899_A2 | Up | 0.9525383171 |
| PubMed_21979375_A1 | Down | -0.3407883200 |
| PubMed_21979375_A2 | Up | 0.6219292337 |
| GSE35957 | Up | 0.2706331820 |
| GSE36640 | Up | 0.7370006903 |
| GSE54402 | Up | 0.1922873331 |
| GSE9593 | Up | 0.1121246950 |
| GSE43922 | Up | 0.0029689388 |
| GSE24585 | Up | 0.3396657362 |
| GSE37065 | Down | -0.0607996095 |
| GSE28863_A1 | Down | -0.0744326688 |
| GSE28863_A2 | Down | -0.0490050088 |
| GSE28863_A3 | Down | -0.2801711433 |
| GSE28863_A4 | Up | 0.0709235180 |
| GSE48662 | Down | -0.0735828947 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027582 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048542 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
