HCSGD entry for COPG1
1. General information
| Official gene symbol | COPG1 |
|---|---|
| Entrez ID | 22820 |
| Gene full name | coatomer protein complex, subunit gamma 1 |
| Other gene symbols | COPG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | ISS | cellular_component |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0030126 | COPI vesicle coat | IEA ISS | cellular_component |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
| GO:0051683 | Establishment of Golgi localization | ISS | biological_process |
| GO:0072384 | Organelle transport along microtubule | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6393347973 | 0.0860382470 | 0.9999902473 | 0.5574998031 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1925669432 |
| GSE13712_SHEAR | Up | 0.1665320105 |
| GSE13712_STATIC | Down | -0.0884132018 |
| GSE19018 | Up | 0.1967412088 |
| GSE19899_A1 | Down | -0.4984444404 |
| GSE19899_A2 | Down | -0.3267867654 |
| PubMed_21979375_A1 | Down | -0.7577858291 |
| PubMed_21979375_A2 | Up | 0.4917304096 |
| GSE35957 | Down | -0.7253115584 |
| GSE36640 | Up | 0.1139964880 |
| GSE54402 | Down | -0.0075504979 |
| GSE9593 | Down | -0.0810310458 |
| GSE43922 | Down | -0.1142870775 |
| GSE24585 | Up | 0.1908651185 |
| GSE37065 | Down | -0.2052513379 |
| GSE28863_A1 | Up | 0.4225283431 |
| GSE28863_A2 | Up | 0.3314827462 |
| GSE28863_A3 | Down | -0.3557586540 |
| GSE28863_A4 | Down | -0.1475949244 |
| GSE48662 | Down | -0.0987384829 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S-(Dimethylarsenic)Cysteine | DB03963 | EXPT00832 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017439 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023687 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023687 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032263 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036123 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049305 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051586 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25220188 | Six genes independently correlated with either age (IL-6, TNFRSF-11B, IGFBP-3, SAA4, and COPG), prognosis (IL-6, SAA4), or the grade of the glioma (IL-6, IL-8, ICAM-1, IGFBP-3, and COPG) |
| 23466301 | These genes, PDIA3, WDR1, FSTL1, COPG1, LMAN1, and PDIA6, significantly downregulated |
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