HCSGD entry for FHL1

1. General information

Official gene symbolFHL1
Entrez ID2273
Gene full namefour and a half LIM domains 1
Other gene symbolsFHL-1 FHL1A FHL1B FLH1A KYOT SLIM SLIM-1 SLIM1 SLIMMER XMPMA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003254Regulation of membrane depolarizationIDAbiological_process
GO:0003674Molecular_functionNDmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007517Muscle organ developmentNASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009887Organ morphogenesisNASbiological_process
GO:0010972Negative regulation of G2/M transition of mitotic cell cycleIDAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0043268Positive regulation of potassium ion transportIDAbiological_process
GO:0044325Ion channel bindingIPImolecular_function
GO:1901016Regulation of potassium ion transmembrane transporter activityIDAbiological_process
GO:2000134Negative regulation of G1/S transition of mitotic cell cycleIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35009081720.00092664030.99999024730.0573718310

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.7817950451
GSE13712_SHEARUp0.8577296230
GSE13712_STATICUp0.2727727852
GSE19018Down-0.1381573337
GSE19899_A1Down-0.9846610353
GSE19899_A2Down-2.4296494257
PubMed_21979375_A1Down-2.0741471990
PubMed_21979375_A2Down-2.0955386336
GSE35957Up0.3034747715
GSE36640Up0.8929630545
GSE54402Down-1.1110578106
GSE9593Up0.0660893250
GSE43922Down-1.3917477950
GSE24585Down-0.9515787594
GSE37065Down-0.3440938033
GSE28863_A1Down-0.2427935297
GSE28863_A2Down-0.5761202206
GSE28863_A3Up0.1051626928
GSE28863_A4Up0.4786000495
GSE48662Up0.4162027902

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019004MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.