HCSGD entry for FGF9

1. General information

Official gene symbolFGF9
Entrez ID2254
Gene full namefibroblast growth factor 9 (glia-activating factor)
Other gene symbolsGAF HBFG-9 SYNS3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0001649Osteoblast differentiationIEAbiological_process
GO:0002053Positive regulation of mesenchymal cell proliferationIEAbiological_process
GO:0002062Chondrocyte differentiationIEAbiological_process
GO:0005104Fibroblast growth factor receptor bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005604Basement membraneIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006606Protein import into nucleusIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008201Heparin bindingIEAmolecular_function
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayIGI TASbiological_process
GO:0008584Male gonad developmentIEPbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0030178Negative regulation of Wnt signaling pathwayIEAbiological_process
GO:0030238Male sex determinationIEAbiological_process
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0030949Positive regulation of vascular endothelial growth factor receptor signaling pathwayIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0043410Positive regulation of MAPK cascadeIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0048505Regulation of timing of cell differentiationIEAbiological_process
GO:0048566Embryonic digestive tract developmentIEAbiological_process
GO:0048706Embryonic skeletal system developmentIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
GO:0060045Positive regulation of cardiac muscle cell proliferationIEAbiological_process
GO:0060484Lung-associated mesenchyme developmentIEAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33830011400.27322668590.99999024730.9994559061

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1901631937
GSE13712_SHEARDown-0.0680639547
GSE13712_STATICUp0.0307382880
GSE19018Down-0.0898094443
GSE19899_A1Up0.0556359735
GSE19899_A2Down-0.1759660062
PubMed_21979375_A1Up0.0921955050
PubMed_21979375_A2Down-0.0466739927
GSE35957Up0.0298360501
GSE36640Up2.2445092380
GSE54402Down-0.7833153740
GSE9593Down-0.0566806641
GSE43922Up0.0129987736
GSE24585Down-0.9088986250
GSE37065Up0.0451626930
GSE28863_A1Up0.1019999132
GSE28863_A2Down-0.0858607265
GSE28863_A3Up0.4407260955
GSE28863_A4Down-0.0214407044
GSE48662Down-0.0215899181

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-140-5pMIMAT0000431MIRT007378Luciferase reporter assayFunctional MTI23401231
hsa-miR-26b-5pMIMAT0000083MIRT029384MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.