HCSGD entry for FGD1

1. General information

Official gene symbolFGD1
Entrez ID2245
Gene full nameFYVE, RhoGEF and PH domain containing 1
Other gene symbolsAAS FGDY MRXS16 ZFYVE3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleISScellular_component
GO:0005085Guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDA ISScellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007010Cytoskeleton organizationISSbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008360Regulation of cell shapeISSbiological_process
GO:0009887Organ morphogenesisTASbiological_process
GO:0030027LamellipodiumISScellular_component
GO:0030036Actin cytoskeleton organizationIDAbiological_process
GO:0031267Small GTPase bindingIDAmolecular_function
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0043088Regulation of Cdc42 GTPase activityIDAbiological_process
GO:0046847Filopodium assemblyIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90563975530.03338846930.99999024730.3454472877

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1994880485
GSE13712_SHEARDown-0.9686635059
GSE13712_STATICDown-1.0405512138
GSE19018Up0.0932722378
GSE19899_A1Down-0.1697994341
GSE19899_A2Down-0.5765794100
PubMed_21979375_A1Down-0.9134490071
PubMed_21979375_A2Down-0.2013438065
GSE35957Down-0.6056887036
GSE36640Down-0.2340646531
GSE54402Up0.3213992782
GSE9593Down-0.3392724358
GSE43922Down-0.0190919322
GSE24585Down-0.5164277282
GSE37065Down-0.1961749452
GSE28863_A1Up0.5033381903
GSE28863_A2Up0.3316407836
GSE28863_A3Down-0.0170294188
GSE28863_A4Down-0.0343773796
GSE48662Up0.1679178409

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.