HCSGD entry for FDXR
1. General information
| Official gene symbol | FDXR |
|---|---|
| Entrez ID | 2232 |
| Gene full name | ferredoxin reductase |
| Other gene symbols | ADXR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004324 | Ferredoxin-NADP+ reductase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA TAS | cellular_component |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006694 | Steroid biosynthetic process | TAS | biological_process |
| GO:0008203 | Cholesterol metabolic process | IEA | biological_process |
| GO:0015039 | NADPH-adrenodoxin reductase activity | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055114 | Oxidation-reduction process | TAS | biological_process |
| GO:0070402 | NADPH binding | IEA | molecular_function |
| GO:0070995 | NADPH oxidation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0063372668 | 0.8922263440 | 0.2108763590 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8532346252 |
| GSE13712_SHEAR | Up | 1.2064947227 |
| GSE13712_STATIC | Up | 1.1793705694 |
| GSE19018 | Up | 0.4547544705 |
| GSE19899_A1 | Up | 0.0214411596 |
| GSE19899_A2 | Up | 0.7487277357 |
| PubMed_21979375_A1 | Up | 0.2831195241 |
| PubMed_21979375_A2 | Up | 0.5192680112 |
| GSE35957 | Down | -0.5699587669 |
| GSE36640 | Up | 0.2655786409 |
| GSE54402 | Down | -0.8171120526 |
| GSE9593 | Down | -0.4895185191 |
| GSE43922 | Up | 0.0361373281 |
| GSE24585 | Up | 0.4267877743 |
| GSE37065 | Up | 0.0218362990 |
| GSE28863_A1 | Down | -0.0797313895 |
| GSE28863_A2 | Down | -0.2643888408 |
| GSE28863_A3 | Up | 0.3889231228 |
| GSE28863_A4 | Up | 0.2230318880 |
| GSE48662 | Up | 0.9707733601 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2'-Monophosphoadenosine 5'-Diphosphoribose | DB03461 | EXPT02293 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029194 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031555 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-501-3p | MIMAT0004774 | MIRT037989 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-500a-3p | MIMAT0002871 | MIRT041149 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
