HCSGD entry for FDX1
1. General information
| Official gene symbol | FDX1 |
|---|---|
| Entrez ID | 2230 |
| Gene full name | ferredoxin 1 |
| Other gene symbols | ADX FDX LOH11CR1D |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | TAS | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006694 | Steroid biosynthetic process | IEA | biological_process |
| GO:0008203 | Cholesterol metabolic process | IDA | biological_process |
| GO:0009055 | Electron carrier activity | IDA | molecular_function |
| GO:0042446 | Hormone biosynthetic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051537 | 2 iron, 2 sulfur cluster binding | IDA | molecular_function |
| GO:0055114 | Oxidation-reduction process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4111052658 | 0.6535266251 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2801439628 |
| GSE13712_SHEAR | Up | 0.0131930344 |
| GSE13712_STATIC | Up | 0.1184613670 |
| GSE19018 | Down | -0.6338432772 |
| GSE19899_A1 | Down | -0.1026332342 |
| GSE19899_A2 | Up | 0.4071788921 |
| PubMed_21979375_A1 | Up | 0.6679630542 |
| PubMed_21979375_A2 | Up | 0.3135202397 |
| GSE35957 | Up | 0.0515822361 |
| GSE36640 | Down | -0.1321330461 |
| GSE54402 | Up | 0.0039465200 |
| GSE9593 | Down | -0.1234074563 |
| GSE43922 | Up | 0.0847562682 |
| GSE24585 | Down | -0.2084776833 |
| GSE37065 | Down | -0.0621485553 |
| GSE28863_A1 | Up | 0.0636146433 |
| GSE28863_A2 | Up | 0.0947232451 |
| GSE28863_A3 | Up | 0.0233824724 |
| GSE28863_A4 | Up | 0.0390385553 |
| GSE48662 | Up | 0.0070590514 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Mitotane | DB00648 | APRD00494 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028451 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037813 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
