HCSGD entry for FCGR3A

1. General information

Official gene symbolFCGR3A
Entrez ID2214
Gene full nameFc fragment of IgG, low affinity IIIa, receptor (CD16a)
Other gene symbolsCD16 CD16A FCG3 FCGR3 FCGRIII FCR-10 FCRIII FCRIIIA IGFR3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019864IgG bindingIEAmolecular_function
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050776Regulation of immune responseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82683040920.91980435010.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.0178024889
GSE24585Down-0.0084714633
GSE37065Down-0.0965209128
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0890511217

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CetuximabDB00002 BTD00071 | BIOD00071
EtanerceptDB00005 BTD00052 | BIOD00052
Immune Globulin HumanDB00028 BTD00091 | BIOD00091
AdalimumabDB00051 BTD00049 | BIOD00049
AbciximabDB00054 BTD00041 | BIOD00041
Gemtuzumab ozogamicinDB00056 BTD00077 | BIOD00077
TrastuzumabDB00072 BTD00098 | BIOD00098
RituximabDB00073 BTD00014 | BIOD00014
BasiliximabDB00074 BTD00073 | BIOD00073
MuromonabDB00075 BTD00005 | BIOD00005
Ibritumomab tiuxetanDB00078 BTD00069 | BIOD00069
TositumomabDB00081 BTD00085 | BIOD00085
AlemtuzumabDB00087 BTD00109 | BIOD00109
AlefaceptDB00092 BTD00055 | BIOD00055
EfalizumabDB00095 BTD00074 | BIOD00074
NatalizumabDB00108 BTD00083 | BIOD00083
PalivizumabDB00110 BTD00097 | BIOD00097
DaclizumabDB00111 BTD00007 | BIOD00007
BevacizumabDB00112 BTD00087 | BIOD00087

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.