HCSGD entry for FCER1G

1. General information

Official gene symbolFCER1G
Entrez ID2207
Gene full nameFc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Other gene symbolsFCRG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001798Positive regulation of type IIa hypersensitivityIEAbiological_process
GO:0001805Positive regulation of type III hypersensitivityIEAbiological_process
GO:0001812Positive regulation of type I hypersensitivityIEAbiological_process
GO:0002283Neutrophil activation involved in immune responseIEAbiological_process
GO:0002431Fc receptor mediated stimulatory signaling pathwayIEAbiological_process
GO:0002554Serotonin secretion by plateletIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006911Phagocytosis, engulfmentIEAbiological_process
GO:0007229Integrin-mediated signaling pathwayIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0010543Regulation of platelet activationIEAbiological_process
GO:0016064Immunoglobulin mediated immune responseIEAbiological_process
GO:0019767IgE receptor activityIEAmolecular_function
GO:0019863IgE bindingIEAmolecular_function
GO:0019864IgG bindingIEAmolecular_function
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IIIEAbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0030593Neutrophil chemotaxisIEAbiological_process
GO:0032733Positive regulation of interleukin-10 productionIEAbiological_process
GO:0032755Positive regulation of interleukin-6 productionIEAbiological_process
GO:0032760Positive regulation of tumor necrosis factor productionIEAbiological_process
GO:0032765Positive regulation of mast cell cytokine productionIEAbiological_process
GO:0032998Fc-epsilon receptor I complexIEAcellular_component
GO:0033026Negative regulation of mast cell apoptotic processIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class IIEAbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0043306Positive regulation of mast cell degranulationIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045576Mast cell activationIEAbiological_process
GO:0050766Positive regulation of phagocytosisIEAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18422017400.89502616920.83933023011.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0659418520
GSE13712_SHEARDown-0.0150667040
GSE13712_STATICUp0.1183157687
GSE19018Down-0.0247226279
GSE19899_A1Up0.1460391474
GSE19899_A2Up0.5058205562
PubMed_21979375_A1Up0.2231589200
PubMed_21979375_A2Up0.4507415676
GSE35957Down-0.0787022798
GSE36640Down-0.0795632049
GSE54402Up0.2152717876
GSE9593Down-0.1613644490
GSE43922Up0.3286849552
GSE24585Down-0.0489688025
GSE37065Up0.2984835610
GSE28863_A1Down-0.0223558101
GSE28863_A2Down-0.0295743884
GSE28863_A3Up0.2183508279
GSE28863_A4Up0.1122462527
GSE48662Down-0.0167590605

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Benzylpenicilloyl PolylysineDB00895 APRD00822

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.