HCSGD entry for FCER1A

1. General information

Official gene symbolFCER1A
Entrez ID2205
Gene full nameFc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Other gene symbolsFCE1A FcERI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001812Positive regulation of type I hypersensitivityIEAbiological_process
GO:0001820Serotonin secretionIEAbiological_process
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007257Activation of JUN kinase activityIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0019370Leukotriene biosynthetic processIEAbiological_process
GO:0019767IgE receptor activityIEAmolecular_function
GO:0019863IgE bindingIEAmolecular_function
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0043306Positive regulation of mast cell degranulationIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045401Positive regulation of interleukin-3 biosynthetic processIEAbiological_process
GO:0045425Positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic processIEAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIEAbiological_process
GO:0050850Positive regulation of calcium-mediated signalingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70229749630.84221644690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0924187015
GSE13712_SHEARUp0.0392780153
GSE13712_STATICUp0.1005868122
GSE19018Up0.0728673557
GSE19899_A1Up0.2107834751
GSE19899_A2Up0.1038170927
PubMed_21979375_A1Up0.0451612861
PubMed_21979375_A2Up0.0492505300
GSE35957Down-0.0809879935
GSE36640Down-0.0343094927
GSE54402Up0.0125932091
GSE9593Down-0.0243042930
GSE43922Up0.0109738489
GSE24585Up0.0635034295
GSE37065Down-0.1813268484
GSE28863_A1Up0.0798529500
GSE28863_A2Up0.1352939912
GSE28863_A3Up0.0555677314
GSE28863_A4Up0.0213734673
GSE48662Up0.0094791130

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OmalizumabDB00043 BTD00081 | BIOD00081
Benzylpenicilloyl PolylysineDB00895 APRD00822
TNX-901DB05797 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.