HCSGD entry for FBP1

1. General information

Official gene symbolFBP1
Entrez ID2203
Gene full namefructose-1,6-bisphosphatase 1
Other gene symbolsFBP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolISS TAScellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0006000Fructose metabolic processTASbiological_process
GO:0006002Fructose 6-phosphate metabolic processIDAbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006094GluconeogenesisIEA IMP ISS TASbiological_process
GO:0006111Regulation of gluconeogenesisIMPbiological_process
GO:0016208AMP bindingIDAmolecular_function
GO:0016311DephosphorylationIDA IMPbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0035690Cellular response to drugIDAbiological_process
GO:0042132Fructose 1,6-bisphosphate 1-phosphatase activityIDA IEA IMPmolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045820Negative regulation of glycolysisIDAbiological_process
GO:0046580Negative regulation of Ras protein signal transductionIDAbiological_process
GO:0046872Metal ion bindingIMPmolecular_function
GO:0048029Monosaccharide bindingISSmolecular_function
GO:0051289Protein homotetramerizationIDAbiological_process
GO:0071286Cellular response to magnesium ionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41900280380.83357106870.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0838429819
GSE13712_SHEARDown-0.1092180772
GSE13712_STATICUp0.1020297469
GSE19018Down-0.1324769426
GSE19899_A1Down-0.1123237774
GSE19899_A2Up0.2109263360
PubMed_21979375_A1Down-0.0642261780
PubMed_21979375_A2Down-0.1857568067
GSE35957Up0.2992191096
GSE36640Up0.0106923406
GSE54402Up0.1449155532
GSE9593Up0.1043859162
GSE43922Up0.0156482577
GSE24585Up0.2633717862
GSE37065Up0.1217532451
GSE28863_A1Up0.2981788101
GSE28863_A2Down-0.0068403341
GSE28863_A3Up0.3043940222
GSE28863_A4Down-0.0458198568
GSE48662Up0.0686354030

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2,5-Anhydroglucitol-1,6-BiphosphateDB02778 EXPT00466
{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-MethanolDB02848 EXPT02557
Mdl-29951DB04175 EXPT00939
Fructose-6-PhosphateDB04493 EXPT01383
MB07803DB05053 -
N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDEDB07270 -
2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDEDB07312 -
2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDEDB07321 -
4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDEDB08484 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.