HCSGD entry for FBLN2
1. General information
| Official gene symbol | FBLN2 |
|---|---|
| Entrez ID | 2199 |
| Gene full name | fibulin 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005201 | Extracellular matrix structural constituent | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0010811 | Positive regulation of cell-substrate adhesion | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031012 | Extracellular matrix | ISS | cellular_component |
| GO:0050840 | Extracellular matrix binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1574167851 | 0.0056288553 | 0.7875626687 | 0.1514385087 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.3282184625 |
| GSE13712_SHEAR | Down | -1.4792826927 |
| GSE13712_STATIC | Down | -0.0024892639 |
| GSE19018 | Up | 0.3770088622 |
| GSE19899_A1 | Down | -0.2182785536 |
| GSE19899_A2 | Down | -0.7262201111 |
| PubMed_21979375_A1 | Down | -1.1687849418 |
| PubMed_21979375_A2 | Down | -0.7595877742 |
| GSE35957 | Up | 0.9381980929 |
| GSE36640 | Down | -1.0148212022 |
| GSE54402 | Down | -1.4679487947 |
| GSE9593 | Down | -0.1764762645 |
| GSE43922 | Down | -0.3679715453 |
| GSE24585 | Up | 0.0295114532 |
| GSE37065 | Down | -0.1471143620 |
| GSE28863_A1 | Up | 0.9691241470 |
| GSE28863_A2 | Up | 0.9575563338 |
| GSE28863_A3 | Up | 0.4815570531 |
| GSE28863_A4 | Down | -0.0839496815 |
| GSE48662 | Up | 0.4554862604 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002753 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018315 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
