HCSGD entry for HYLS1
1. General information
| Official gene symbol | HYLS1 |
|---|---|
| Entrez ID | 219844 |
| Gene full name | hydrolethalus syndrome 1 |
| Other gene symbols | HLS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9166712435 | 0.0038787318 | 0.9999902473 | 0.1266651365 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0298160392 |
| GSE13712_SHEAR | Up | 0.0679308030 |
| GSE13712_STATIC | Up | 0.1512554261 |
| GSE19018 | Down | -0.3446075246 |
| GSE19899_A1 | Down | -0.5195598526 |
| GSE19899_A2 | Down | -1.1027352039 |
| PubMed_21979375_A1 | Up | 0.2977991883 |
| PubMed_21979375_A2 | Down | -1.3113756200 |
| GSE35957 | Down | -1.8282177237 |
| GSE36640 | Down | -2.0984558741 |
| GSE54402 | Down | -0.2088033378 |
| GSE9593 | Down | -0.6615407749 |
| GSE43922 | Down | -0.0667519627 |
| GSE24585 | Down | -0.2746911405 |
| GSE37065 | Up | 0.0683028337 |
| GSE28863_A1 | Down | -0.1347052769 |
| GSE28863_A2 | Down | -0.2252721432 |
| GSE28863_A3 | Down | -0.4287362660 |
| GSE28863_A4 | Up | 0.4994766800 |
| GSE48662 | Down | -0.9137248302 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024355 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026915 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-1303 | MIMAT0005891 | MIRT035897 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
