HCSGD entry for FARSA
1. General information
| Official gene symbol | FARSA |
|---|---|
| Entrez ID | 2193 |
| Gene full name | phenylalanyl-tRNA synthetase, alpha subunit |
| Other gene symbols | CML33 FARSL FARSLA FRSA PheHA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IEA | molecular_function |
| GO:0004812 | Aminoacyl-tRNA ligase activity | IEA | molecular_function |
| GO:0004826 | Phenylalanine-tRNA ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006432 | Phenylalanyl-tRNA aminoacylation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0043039 | TRNA aminoacylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0202339159 | 0.7581505186 | 0.3424931833 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3668097843 |
| GSE13712_SHEAR | Up | 0.2122731636 |
| GSE13712_STATIC | Up | 0.4278077457 |
| GSE19018 | Down | -0.4686786295 |
| GSE19899_A1 | Up | 0.3360847579 |
| GSE19899_A2 | Up | 1.0600691210 |
| PubMed_21979375_A1 | Up | 2.2811567947 |
| PubMed_21979375_A2 | Up | 0.6088036243 |
| GSE35957 | Down | -0.3791734588 |
| GSE36640 | Down | -0.2136530547 |
| GSE54402 | Up | 0.8862270341 |
| GSE9593 | Down | -0.6475864427 |
| GSE43922 | Up | 0.3512905703 |
| GSE24585 | Down | -0.4384644792 |
| GSE37065 | Down | -0.0065559886 |
| GSE28863_A1 | Down | -0.1709691981 |
| GSE28863_A2 | Up | 0.0230524654 |
| GSE28863_A3 | Up | 0.1638027259 |
| GSE28863_A4 | Up | 0.0170348009 |
| GSE48662 | Up | 0.2243395170 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Phenylalanine | DB00120 | NUTR00044 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-503-5p | MIMAT0002874 | MIRT041106 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041766 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046922 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052471 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
