HCSGD entry for FANCG
1. General information
| Official gene symbol | FANCG |
|---|---|
| Entrez ID | 2189 |
| Gene full name | Fanconi anemia, complementation group G |
| Other gene symbols | FAG XRCC9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000075 | Cell cycle checkpoint | TAS | biological_process |
| GO:0001541 | Ovarian follicle development | IEA | biological_process |
| GO:0003684 | Damaged DNA binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IEA | biological_process |
| GO:0007005 | Mitochondrion organization | IMP | biological_process |
| GO:0007286 | Spermatid development | IEA | biological_process |
| GO:0009314 | Response to radiation | IEA | biological_process |
| GO:0043240 | Fanconi anaemia nuclear complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9925871547 | 0.0008640363 | 0.9999902473 | 0.0561538272 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4101680466 |
| GSE13712_SHEAR | Down | -0.5158071537 |
| GSE13712_STATIC | Down | -0.4182649850 |
| GSE19018 | Up | 0.0385287232 |
| GSE19899_A1 | Down | -0.7030118279 |
| GSE19899_A2 | Down | -2.1274311846 |
| PubMed_21979375_A1 | Down | -1.8334028275 |
| PubMed_21979375_A2 | Down | -2.9179700255 |
| GSE35957 | Down | -1.2799818321 |
| GSE36640 | Down | -2.8228233327 |
| GSE54402 | Down | -0.3487906556 |
| GSE9593 | Down | -1.5438892629 |
| GSE43922 | Down | -0.2529482273 |
| GSE24585 | Up | 0.1249561824 |
| GSE37065 | Down | -0.2357446308 |
| GSE28863_A1 | Up | 0.1517121632 |
| GSE28863_A2 | Up | 0.1241241088 |
| GSE28863_A3 | Down | -0.1157958553 |
| GSE28863_A4 | Up | 0.0678043886 |
| GSE48662 | Down | -0.4589010010 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT006898 | Immunoblot//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 21750350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016405 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037687 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
