HCSGD entry for ALDH3A1

1. General information

Official gene symbolALDH3A1
Entrez ID218
Gene full namealdehyde dehydrogenase 3 family, member A1
Other gene symbolsALDH3 ALDHIII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:00040283-chloroallyl aldehyde dehydrogenase activityIEAmolecular_function
GO:0004029Aldehyde dehydrogenase (NAD) activityIDAmolecular_function
GO:0004030Aldehyde dehydrogenase [NAD(P)+] activityIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005829CytosolIEA ISScellular_component
GO:0006081Cellular aldehyde metabolic processIDA IEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0008106Alcohol dehydrogenase (NADP+) activityIDAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29275155580.87774379390.99297856961.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1061060731
GSE13712_SHEARDown-0.0187610023
GSE13712_STATICUp0.0633378561
GSE19018Up0.0855532044
GSE19899_A1Up0.0058872305
GSE19899_A2Up0.3121001704
PubMed_21979375_A1Up0.1649005769
PubMed_21979375_A2Up0.0104274801
GSE35957Down-0.3924931153
GSE36640Down-0.0620463015
GSE54402Up0.0681053712
GSE9593Up1.0055655549
GSE43922Up0.0282956150
GSE24585Down-0.1723874836
GSE37065Up0.0580781087
GSE28863_A1Down-0.0326684375
GSE28863_A2Up0.0243521505
GSE28863_A3Up0.2693306270
GSE28863_A4Up0.1085109681
GSE48662Up0.2183236589

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021523Reporter assay;MicroarrayFunctional MTI21351259
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.