HCSGD entry for EXTL3
1. General information
| Official gene symbol | EXTL3 |
|---|---|
| Entrez ID | 2137 |
| Gene full name | exostosin-like glycosyltransferase 3 |
| Other gene symbols | BOTV EXTR1 REGR RPR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001888 | Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0015012 | Heparan sulfate proteoglycan biosynthetic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016758 | Transferase activity, transferring hexosyl groups | IEA | molecular_function |
| GO:0030307 | Positive regulation of cell growth | IEA | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0031227 | Intrinsic component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0215028570 | 0.8231675354 | 0.3532938202 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0306733355 |
| GSE13712_SHEAR | Up | 0.0083387174 |
| GSE13712_STATIC | Up | 0.2344506298 |
| GSE19018 | Up | 0.1317485604 |
| GSE19899_A1 | Up | 0.1557428005 |
| GSE19899_A2 | Up | 0.6235661499 |
| PubMed_21979375_A1 | Up | 1.1348887410 |
| PubMed_21979375_A2 | Up | 0.8073999214 |
| GSE35957 | Up | 0.1438426160 |
| GSE36640 | Up | 0.2595226212 |
| GSE54402 | Up | 0.4405571852 |
| GSE9593 | Up | 0.1174456461 |
| GSE43922 | Up | 0.8912979612 |
| GSE24585 | Down | -0.1653594017 |
| GSE37065 | Up | 0.0091533400 |
| GSE28863_A1 | Up | 0.1794621829 |
| GSE28863_A2 | Up | 0.5772956281 |
| GSE28863_A3 | Down | -0.7103518382 |
| GSE28863_A4 | Down | -0.3683087418 |
| GSE48662 | Up | 0.0340662988 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018750 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-500a-5p | MIMAT0004773 | MIRT037996 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046048 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047402 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047509 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048650 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
