HCSGD entry for ALB

1. General information

Official gene symbolALB
Entrez ID213
Gene full namealbumin
Other gene symbolsPRO0883 PRO0903 PRO1341
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002576Platelet degranulationTASbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0005504Fatty acid bindingIDA NASmolecular_function
GO:0005507Copper ion bindingNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005604Basement membraneIEAcellular_component
GO:0005615Extracellular spaceIDA IEAcellular_component
GO:0006810TransportIEA TASbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008144Drug bindingIDA NASmolecular_function
GO:0008206Bile acid metabolic processTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009267Cellular response to starvationIDAbiological_process
GO:0010033Response to organic substanceIEAbiological_process
GO:0015643Toxic substance bindingIDAmolecular_function
GO:0015721Bile acid and bile salt transportTASbiological_process
GO:0016209Antioxidant activityNASmolecular_function
GO:0019825Oxygen bindingIDAmolecular_function
GO:0019836Hemolysis by symbiont of host erythrocytesIDAbiological_process
GO:0019899Enzyme bindingIEAmolecular_function
GO:0030168Platelet activationTASbiological_process
GO:0030170Pyridoxal phosphate bindingIDAmolecular_function
GO:0031093Platelet alpha granule lumenTAScellular_component
GO:0042157Lipoprotein metabolic processTASbiological_process
GO:0043066Negative regulation of apoptotic processIDAbiological_process
GO:0043069Negative regulation of programmed cell deathNASbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0043252Sodium-independent organic anion transportTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046010Positive regulation of circadian sleep/wake cycle, non-REM sleepIEAbiological_process
GO:0046689Response to mercury ionIEAbiological_process
GO:0051087Chaperone bindingIPImolecular_function
GO:0051659Maintenance of mitochondrion locationIDAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070062Extracellular vesicular exosomeIDAcellular_component
GO:0070541Response to platinum ionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90065644920.73737802140.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0218479007
GSE13712_SHEARDown-0.0580274191
GSE13712_STATICDown-0.1002573711
GSE19018Up0.0526165923
GSE19899_A1Up0.1502382119
GSE19899_A2Down-0.0673846178
PubMed_21979375_A1Up0.0877009446
PubMed_21979375_A2Down-0.0044417173
GSE35957Up0.0194042930
GSE36640Up0.1048709719
GSE54402Down-0.0066193628
GSE9593Down-0.0988630845
GSE43922Up0.0120147115
GSE24585Down-0.1311306236
GSE37065Down-0.0938475625
GSE28863_A1Up0.0546308881
GSE28863_A2Up0.0955811572
GSE28863_A3Up0.0129518997
GSE28863_A4Down-0.0002673632
GSE48662Down-0.0995827060

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

RifampicinDB01045 APRD00207 | EXPT02777

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 4 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23833691METHODS: Human umbilical cord blood derived endothelial cells (hCB-ECs) and human aortic endothelial cells (HAECs) were treated with 200 muM H2O2 and permeability to FITC-bovine serum albumin was measured
22511839METHODS: Primarily cultured HTMC were exposed to 0, 10, 50, 100, 200 microg/mL of glycated bovine serum albumin (G-BSA) for 5 days
7592769The 66-kDa protein was identified to be serum albumin by immunoblot analysis
15374429Addition of various molecules (bovine serum albumin, egg albumin, dextrane, starch and PEG-8000) in increasing concentrations up to greater than 20% by volume decreased the rate of oxygen evolution in a linear fashion, although there were some quantitative differences between the effects of various components
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