HCSGD entry for ESRRG

1. General information

Official gene symbolESRRG
Entrez ID2104
Gene full nameestrogen-related receptor gamma
Other gene symbolsERR3 ERRgamma NR3B3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0003708Retinoic acid receptor activityIEAmolecular_function
GO:0005496Steroid bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIEA ISSbiological_process
GO:0050682AF-2 domain bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54317873180.74271725620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0442843293
GSE13712_SHEARUp0.0525260739
GSE13712_STATICUp0.1040297702
GSE19018Up0.0794993605
GSE19899_A1Up0.0943061699
GSE19899_A2Down-0.2519938029
PubMed_21979375_A1Down-0.5235473988
PubMed_21979375_A2Up0.5038044668
GSE35957Up0.0909936358
GSE36640Up0.2445775939
GSE54402Down-0.3300441169
GSE9593Up0.0149215785
GSE43922Up0.0138250080
GSE24585Up0.0810776861
GSE37065Up0.0337661202
GSE28863_A1Down-0.1262800940
GSE28863_A2Down-0.0861122857
GSE28863_A3Up0.1537129105
GSE28863_A4Down-0.0022427883
GSE48662Up0.4186542448

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TroglitazoneDB00197 APRD00488
Cholic AcidDB02659 EXPT00906
AfimoxifeneDB04468 EXPT02425
4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDEDB06884 -
4-(1-methyl-1-phenylethyl)phenolDB06902 -
4,4'-PROPANE-2,2-DIYLDIPHENOLDB06973 -
4,4'-cyclohexane-1,1-diyldiphenolDB07485 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.