HCSGD entry for ABCA3
1. General information
| Official gene symbol | ABCA3 |
|---|---|
| Entrez ID | 21 |
| Gene full name | ATP-binding cassette, sub-family A (ABC1), member 3 |
| Other gene symbols | ABC-C ABC3 EST111653 LBM180 SMDP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006810 | Transport | IDA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016887 | ATPase activity | IEA | molecular_function |
| GO:0042493 | Response to drug | TAS | biological_process |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | TAS | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0097208 | Alveolar lamellar body | IDA | cellular_component |
| GO:0097233 | Alveolar lamellar body membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0077729038 | 0.9750545724 | 0.2284627232 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1844569197 |
| GSE13712_SHEAR | Down | -0.0388682667 |
| GSE13712_STATIC | Up | 0.1718159746 |
| GSE19018 | Up | 0.0423501780 |
| GSE19899_A1 | Up | 0.3787199299 |
| GSE19899_A2 | Up | 1.6522642104 |
| PubMed_21979375_A1 | Up | 1.5563648019 |
| PubMed_21979375_A2 | Up | 1.1896660196 |
| GSE35957 | Down | -0.0024221602 |
| GSE36640 | Up | 0.6305853567 |
| GSE54402 | Down | -0.0065915670 |
| GSE9593 | Up | 0.0519831739 |
| GSE43922 | Up | 1.4022198184 |
| GSE24585 | Down | -0.4037928966 |
| GSE37065 | Up | 0.1352344394 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4672218296 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016946 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040559 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049276 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050565 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
