HCSGD entry for ESD
1. General information
| Official gene symbol | ESD |
|---|---|
| Entrez ID | 2098 |
| Gene full name | esterase D |
| Other gene symbols | FGH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0018738 | S-formylglutathione hydrolase activity | IEA | molecular_function |
| GO:0046294 | Formaldehyde catabolic process | IEA | biological_process |
| GO:0047374 | Methylumbelliferyl-acetate deacetylase activity | IEA | molecular_function |
| GO:0052689 | Carboxylic ester hydrolase activity | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9901764181 | 0.0279281980 | 0.9999902473 | 0.3179322093 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0702833987 |
| GSE13712_SHEAR | Down | -0.0537387384 |
| GSE13712_STATIC | Up | 0.0380562693 |
| GSE19018 | Up | 0.0336616359 |
| GSE19899_A1 | Down | -0.3325081921 |
| GSE19899_A2 | Down | -0.3132843563 |
| PubMed_21979375_A1 | Down | -0.5099054424 |
| PubMed_21979375_A2 | Down | -0.7395022561 |
| GSE35957 | Up | 0.0326016906 |
| GSE36640 | Up | 0.0441307097 |
| GSE54402 | Down | -0.2368521471 |
| GSE9593 | Down | -0.0911535124 |
| GSE43922 | Down | -0.6132669076 |
| GSE24585 | Down | -0.4001529990 |
| GSE37065 | Down | -0.0686801619 |
| GSE28863_A1 | Down | -0.1791111925 |
| GSE28863_A2 | Down | -0.1648028019 |
| GSE28863_A3 | Down | -0.4748569551 |
| GSE28863_A4 | Up | 0.1426584927 |
| GSE48662 | Down | -0.3700243007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041306 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043244 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045577 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049564 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
