HCSGD entry for EPOR

1. General information

Official gene symbolEPOR
Entrez ID2057
Gene full nameerythropoietin receptor
Other gene symbolsEPO-R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityIEAmolecular_function
GO:0004900Erythropoietin receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007165Signal transductionNASbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0009790Embryo developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayIDA TASbiological_process
GO:0038162Erythropoietin-mediated signaling pathwayIDA TASbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0046697DecidualizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22705418870.54955434060.90850022801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0773062988
GSE13712_SHEARDown-0.7259759119
GSE13712_STATICDown-0.3996046970
GSE19018Up0.4715046407
GSE19899_A1Up0.1198073650
GSE19899_A2Down-0.0326993959
PubMed_21979375_A1Up0.1868992721
PubMed_21979375_A2Down-0.3599816680
GSE35957Down-0.3280533680
GSE36640Down-0.0248760807
GSE54402Up0.2280256840
GSE9593Up0.1286637934
GSE43922Up0.0381345167
GSE24585Up0.3644726639
GSE37065Up0.2170082961
GSE28863_A1Up0.0116305853
GSE28863_A2Up0.4872788098
GSE28863_A3Up0.0227918022
GSE28863_A4Down-0.1557891683
GSE48662Down-0.0710992092

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Darbepoetin alfaDB00012 BTD00032 | BIOD00032
3,5 DIBROMOTYROSINEDB07637 -
PeginesatideDB08894 -
Epoetin ZetaDB08923 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018029MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.