HCSGD entry for EPHX1
1. General information
| Official gene symbol | EPHX1 |
|---|---|
| Entrez ID | 2052 |
| Gene full name | epoxide hydrolase 1, microsomal (xenobiotic) |
| Other gene symbols | EPHX EPOX HYL1 MEH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004301 | Epoxide hydrolase activity | TAS | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006725 | Cellular aromatic compound metabolic process | IEA | biological_process |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0014070 | Response to organic cyclic compound | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019439 | Aromatic compound catabolic process | IEA | biological_process |
| GO:0033961 | Cis-stilbene-oxide hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0163305156 | 0.0363881122 | 0.3144370885 | 0.3595238363 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.3791821621 |
| GSE13712_SHEAR | Down | -1.6840806590 |
| GSE13712_STATIC | Down | -0.0959367904 |
| GSE19018 | Down | -0.8855062110 |
| GSE19899_A1 | Down | -0.4349386925 |
| GSE19899_A2 | Down | -0.1336128699 |
| PubMed_21979375_A1 | Down | -1.0205443053 |
| PubMed_21979375_A2 | Up | 2.0539702037 |
| GSE35957 | Down | -0.2526140489 |
| GSE36640 | Up | 1.3357434298 |
| GSE54402 | Down | -0.2850459944 |
| GSE9593 | Up | 0.5931798872 |
| GSE43922 | Down | -0.5961629919 |
| GSE24585 | Up | 0.8317734989 |
| GSE37065 | Down | -0.0498466648 |
| GSE28863_A1 | Up | 0.7107091471 |
| GSE28863_A2 | Up | 0.2541452017 |
| GSE28863_A3 | Down | -0.1898291716 |
| GSE28863_A4 | Down | -0.2544661108 |
| GSE48662 | Up | 0.9087502061 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016561 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030149 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
