HCSGD entry for EPHA8

1. General information

Official gene symbolEPHA8
Entrez ID2046
Gene full nameEPH receptor A8
Other gene symbolsEEK EK3 HEK3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005004GPI-linked ephrin receptor activityISSmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneISScellular_component
GO:0006929Substrate-dependent cell migrationISSbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007411Axon guidanceISSbiological_process
GO:0016322Neuron remodelingISSbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationISSbiological_process
GO:0030155Regulation of cell adhesionISSbiological_process
GO:0031175Neuron projection developmentISSbiological_process
GO:0031901Early endosome membraneIEAcellular_component
GO:0033628Regulation of cell adhesion mediated by integrinISSbiological_process
GO:0043005Neuron projectionISScellular_component
GO:0043410Positive regulation of MAPK cascadeISSbiological_process
GO:0043552Positive regulation of phosphatidylinositol 3-kinase activityISSbiological_process
GO:0046777Protein autophosphorylationISSbiological_process
GO:0048013Ephrin receptor signaling pathwayISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71097880020.79878674440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0491560262
GSE13712_SHEARDown-0.1176356296
GSE13712_STATICDown-0.0414698202
GSE19018Up0.0109479791
GSE19899_A1Up0.0959072909
GSE19899_A2Up0.2421578950
PubMed_21979375_A1Up0.0410846483
PubMed_21979375_A2Down-0.0306940309
GSE35957Up0.1450817793
GSE36640Up0.0487050777
GSE54402Down-0.0110484582
GSE9593Up0.0243481545
GSE43922Up0.0489127848
GSE24585Down-0.2555017135
GSE37065Down-0.0908725423
GSE28863_A1Down-0.0702142033
GSE28863_A2Up0.1230394322
GSE28863_A3Up0.3276964006
GSE28863_A4Up0.0647195696
GSE48662Down-0.0378580025

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.