HCSGD entry for CERS3
1. General information
| Official gene symbol | CERS3 |
|---|---|
| Entrez ID | 204219 |
| Gene full name | ceramide synthase 3 |
| Other gene symbols | LASS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030148 | Sphingolipid biosynthetic process | IEA TAS | biological_process |
| GO:0030216 | Keratinocyte differentiation | IMP | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IMP | biological_process |
| GO:0050291 | Sphingosine N-acyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7489046085 | 0.6828886440 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1562437089 |
| GSE13712_SHEAR | Down | -0.0352808221 |
| GSE13712_STATIC | Down | -0.2183258995 |
| GSE19018 | Up | 0.0205317255 |
| GSE19899_A1 | Up | 0.1857881217 |
| GSE19899_A2 | Down | -0.0038230665 |
| PubMed_21979375_A1 | Up | 0.1687087385 |
| PubMed_21979375_A2 | Down | -0.1691530391 |
| GSE35957 | Up | 0.2827583963 |
| GSE36640 | Down | -0.0228237318 |
| GSE54402 | Up | 0.0092142676 |
| GSE9593 | Down | -0.0588331652 |
| GSE43922 | Up | 0.0913499028 |
| GSE24585 | Down | -0.1629647591 |
| GSE37065 | Down | -0.1164685592 |
| GSE28863_A1 | Down | -0.0976440191 |
| GSE28863_A2 | Down | -0.0996160427 |
| GSE28863_A3 | Up | 0.1686988688 |
| GSE28863_A4 | Down | -0.0435399068 |
| GSE48662 | Up | 0.1225749653 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
