HCSGD entry for EPHA1

1. General information

Official gene symbolEPHA1
Entrez ID2041
Gene full nameEPH receptor A1
Other gene symbolsEPH EPHT EPHT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001954Positive regulation of cell-matrix adhesionIDAbiological_process
GO:0004672Protein kinase activityIDAmolecular_function
GO:0005005Transmembrane-ephrin receptor activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0007166Cell surface receptor signaling pathwayIDAbiological_process
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030335Positive regulation of cell migrationIMPbiological_process
GO:0030336Negative regulation of cell migrationIDAbiological_process
GO:0032314Regulation of Rac GTPase activityIDAbiological_process
GO:0032862Activation of Rho GTPase activityIDAbiological_process
GO:0034446Substrate adhesion-dependent cell spreadingIDAbiological_process
GO:0045766Positive regulation of angiogenesisIMPbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0051496Positive regulation of stress fiber assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52876659320.94173724400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0472741919
GSE13712_SHEARUp0.0247058740
GSE13712_STATICDown-0.0351542190
GSE19018Up0.0580562365
GSE19899_A1Up0.0428382449
GSE19899_A2Up0.0630113249
PubMed_21979375_A1Up0.1203348042
PubMed_21979375_A2Down-0.0126078696
GSE35957Up0.2488392429
GSE36640Up0.0738139621
GSE54402Up0.0888530584
GSE9593Up0.1077633503
GSE43922Up0.0763932546
GSE24585Up0.2435232488
GSE37065Down-0.0941786663
GSE28863_A1Down-0.0188568957
GSE28863_A2Up0.0693671152
GSE28863_A3Up0.1796701439
GSE28863_A4Down-0.0721788399
GSE48662Down-0.0007976528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017674MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.