HCSGD entry for PTPLB
1. General information
| Official gene symbol | PTPLB |
|---|---|
| Entrez ID | 201562 |
| Gene full name | protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b |
| Other gene symbols | HACD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016829 | Lyase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7526617340 | 0.0634652065 | 0.9999902473 | 0.4749189028 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0244643371 |
| GSE13712_SHEAR | Down | -0.1153229139 |
| GSE13712_STATIC | Up | 0.1739361050 |
| GSE19018 | Down | -0.3697541288 |
| GSE19899_A1 | Down | -0.0379188117 |
| GSE19899_A2 | Down | -0.4177051253 |
| PubMed_21979375_A1 | Down | -0.5923268726 |
| PubMed_21979375_A2 | Up | 0.1505397861 |
| GSE35957 | Up | 0.4191305691 |
| GSE36640 | Up | 0.3141542156 |
| GSE54402 | Down | -0.1994707056 |
| GSE9593 | Down | -0.1243079413 |
| GSE43922 | Up | 0.0087666973 |
| GSE24585 | Up | 0.1437773671 |
| GSE37065 | Down | -0.1654680307 |
| GSE28863_A1 | Down | -0.3733291792 |
| GSE28863_A2 | Down | -0.1569760688 |
| GSE28863_A3 | Down | -0.7474506884 |
| GSE28863_A4 | Down | -0.2673305381 |
| GSE48662 | Up | 0.5661487423 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001341 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016596 | Proteomics | Functional MTI (Weak) | 21512034 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
