HCSGD entry for ELK3
1. General information
| Official gene symbol | ELK3 |
|---|---|
| Entrez ID | 2004 |
| Gene full name | ELK3, ETS-domain protein (SRF accessory protein 2) |
| Other gene symbols | ERP NET SAP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0032422 | Purine-rich negative regulatory element binding | IDA | molecular_function |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1964095437 | 0.2105698302 | 0.8577431486 | 0.8862181804 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2295586697 |
| GSE13712_SHEAR | Down | -1.0783855338 |
| GSE13712_STATIC | Down | -0.6951628258 |
| GSE19018 | Up | 0.1310035958 |
| GSE19899_A1 | Down | -0.1083378016 |
| GSE19899_A2 | Up | 0.5792593352 |
| PubMed_21979375_A1 | Down | -0.2692001386 |
| PubMed_21979375_A2 | Down | -0.4909314410 |
| GSE35957 | Up | 0.0742860362 |
| GSE36640 | Down | -0.2484038317 |
| GSE54402 | Up | 0.6992417895 |
| GSE9593 | Up | 0.5782149602 |
| GSE43922 | Down | -0.6235836167 |
| GSE24585 | Up | 0.3416025747 |
| GSE37065 | Up | 0.0598958787 |
| GSE28863_A1 | Up | 0.1531541192 |
| GSE28863_A2 | Up | 0.3984982310 |
| GSE28863_A3 | Up | 0.0957096893 |
| GSE28863_A4 | Up | 0.0139891972 |
| GSE48662 | Down | -0.3354217950 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003178 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT003523 | Luciferase reporter assay | Functional MTI | 20144220 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT003523 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016563 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020463 | Microarray | Functional MTI (Weak) | 17242205 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
