HCSGD entry for ELF4


1. General information

Official gene symbolELF4
Entrez ID2000
Gene full nameE74-like factor 4 (ets domain transcription factor)
Other gene symbolsELFR MEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001787Natural killer cell proliferationIEA ISSbiological_process
GO:0001866NK T cell proliferationIEA ISSbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89045772580.02955033240.99999024730.3257851171

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1377229769
GSE13712_SHEARDown-0.0543607191
GSE13712_STATICUp0.2064854646
GSE19018Down-0.1553585215
GSE19899_A1Down-0.7413322288
GSE19899_A2Down-0.7243112760
PubMed_21979375_A1Down-0.5130077540
PubMed_21979375_A2Up0.0513837858
GSE35957Down-0.6648928290
GSE36640Down-0.8170686162
GSE54402Down-0.4847637614
GSE9593Down-0.2006554867
GSE43922Down-0.2357537252
GSE24585Down-0.0842125901
GSE37065Down-0.0811276739
GSE28863_A1Up0.7086998163
GSE28863_A2Up0.5204773299
GSE28863_A3Down-0.2813460525
GSE28863_A4Down-0.1594521048
GSE48662Up0.0575403940

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002580MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002580MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029730MicroarrayFunctional MTI (Weak)19088304
hsa-miR-877-5pMIMAT0004949MIRT037325CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039637CLASHFunctional MTI (Weak)23622248
hsa-miR-505-3pMIMAT0002876MIRT041006CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049601CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050308CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.