HCSGD entry for ABCA2

1. General information

Official gene symbolABCA2
Entrez ID20
Gene full nameATP-binding cassette, sub-family A (ABC1), member 2
Other gene symbolsABC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingRCAmolecular_function
GO:0005524ATP bindingIDA IEA ISSmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneRCAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0005815Microtubule organizing centerISScellular_component
GO:0006200ATP catabolic processIDA NASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006629Lipid metabolic processNASbiological_process
GO:0006810TransportNASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0016021Integral component of membraneIDA RCAcellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleISScellular_component
GO:0016887ATPase activityIDA IEAmolecular_function
GO:0032383Regulation of intracellular cholesterol transportIMPbiological_process
GO:0042493Response to drugTASbiological_process
GO:0042626ATPase activity, coupled to transmembrane movement of substancesNASmolecular_function
GO:0042632Cholesterol homeostasisIEPbiological_process
GO:0043190ATP-binding cassette (ABC) transporter complexNAScellular_component
GO:0048545Response to steroid hormoneIEPbiological_process
GO:0055085Transmembrane transportNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22916665780.79047914970.91171340691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1714902056
GSE13712_SHEARDown-0.4516146549
GSE13712_STATICDown-0.2159745433
GSE19018Up0.1101804376
GSE19899_A1Up0.0559326861
GSE19899_A2Up0.1069414730
PubMed_21979375_A1Down-0.0378396588
PubMed_21979375_A2Up0.3168485310
GSE35957Down-0.0230063737
GSE36640Up0.1235413190
GSE54402Down-0.0080719009
GSE9593Up0.1855024762
GSE43922Up0.0603978107
GSE24585Down-0.1071110238
GSE37065Down-0.2657603313
GSE28863_A1Up0.3499919070
GSE28863_A2Up0.1301819721
GSE28863_A3Up0.4025800728
GSE28863_A4Up0.1705860002
GSE48662Up0.5080692943

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.