HCSGD entry for ELF2


1. General information

Official gene symbolELF2
Entrez ID1998
Gene full nameE74-like factor 2 (ets domain transcription factor)
Other gene symbolsEU32 NERF NERF-1A NERF-1B NERF-1a,b NERF-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIC IDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0043565Sequence-specific DNA bindingIDA IEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94626208730.07006097410.99999024730.4997492954

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0223977633
GSE13712_SHEARUp0.0224978847
GSE13712_STATICDown-0.2337093340
GSE19018Up0.2597554829
GSE19899_A1Down-0.0928651657
GSE19899_A2Down-0.6799803321
PubMed_21979375_A1Down-0.2911840126
PubMed_21979375_A2Down-0.5026357760
GSE35957Down-0.1391904400
GSE36640Down-0.5332841876
GSE54402Down-0.2561873671
GSE9593Down-0.3012635976
GSE43922Down-0.2901959474
GSE24585Up0.3847667338
GSE37065Up0.0980238053
GSE28863_A1Down-0.0244223063
GSE28863_A2Up0.1371919783
GSE28863_A3Down-0.0459072163
GSE28863_A4Down-0.1590512057
GSE48662Down-0.0381000020

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.