HCSGD entry for SERPINB1
1. General information
| Official gene symbol | SERPINB1 |
|---|---|
| Entrez ID | 1992 |
| Gene full name | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| Other gene symbols | EI ELANH2 LEI M/NEI MNEI PI-2 PI2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IBA NAS | molecular_function |
| GO:0005615 | Extracellular space | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | IBA | biological_process |
| GO:0030162 | Regulation of proteolysis | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1791159872 | 0.2157191596 | 0.8294355911 | 0.8952380104 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1976604977 |
| GSE13712_SHEAR | Up | 0.3252131670 |
| GSE13712_STATIC | Up | 0.2866196442 |
| GSE19018 | Up | 0.0420069556 |
| GSE19899_A1 | Down | -0.5718544712 |
| GSE19899_A2 | Up | 0.2265739526 |
| PubMed_21979375_A1 | Down | -0.3846512962 |
| PubMed_21979375_A2 | Down | -0.0636795188 |
| GSE35957 | Down | -0.1060458230 |
| GSE36640 | Up | 0.2155255899 |
| GSE54402 | Down | -0.7262097909 |
| GSE9593 | Down | -0.0036507576 |
| GSE43922 | Down | -0.2722338699 |
| GSE24585 | Up | 1.1564534437 |
| GSE37065 | Up | 0.4059384750 |
| GSE28863_A1 | Up | 0.2194165960 |
| GSE28863_A2 | Up | 0.3222462001 |
| GSE28863_A3 | Down | -0.5447297179 |
| GSE28863_A4 | Down | -0.0483092444 |
| GSE48662 | Down | -0.3805092483 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017458 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025408 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029265 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
