HCSGD entry for NSMCE1
1. General information
| Official gene symbol | NSMCE1 |
|---|---|
| Entrez ID | 197370 |
| Gene full name | non-SMC element 1 homolog (S. cerevisiae) |
| Other gene symbols | NSE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000781 | Chromosome, telomeric region | IEA | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006310 | DNA recombination | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0030915 | Smc5-Smc6 complex | IDA IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:2001022 | Positive regulation of response to DNA damage stimulus | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9662025797 | 0.0277213822 | 0.9999902473 | 0.3169559896 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0403143262 |
| GSE13712_SHEAR | Down | -0.5789320155 |
| GSE13712_STATIC | Down | -0.3434471723 |
| GSE19018 | Down | -0.0682308603 |
| GSE19899_A1 | Down | -0.4293484950 |
| GSE19899_A2 | Down | -0.1660852384 |
| PubMed_21979375_A1 | Down | -0.3136529552 |
| PubMed_21979375_A2 | Down | -0.4969652270 |
| GSE35957 | Down | -0.5450399106 |
| GSE36640 | Up | 0.2329471519 |
| GSE54402 | Down | -0.2348288868 |
| GSE9593 | Down | -0.0677595430 |
| GSE43922 | Down | -0.1167873826 |
| GSE24585 | Down | -0.3023239488 |
| GSE37065 | Down | -0.3355787485 |
| GSE28863_A1 | Up | 0.0344857924 |
| GSE28863_A2 | Down | -0.2575770804 |
| GSE28863_A3 | Down | -0.2973950220 |
| GSE28863_A4 | Up | 0.2553912786 |
| GSE48662 | Up | 0.1534789196 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
