HCSGD entry for LCTL

1. General information

Official gene symbolLCTL
Entrez ID197021
Gene full namelactase-like
Other gene symbolsKLG KLPH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97722504080.01030605980.99999024730.2004076527

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0393833026
GSE13712_SHEARUp0.2642213360
GSE13712_STATICDown-0.0507293028
GSE19018Up0.1867032747
GSE19899_A1Down-0.5042042878
GSE19899_A2Down-0.9267434293
PubMed_21979375_A1Down-0.6842758275
PubMed_21979375_A2Down-0.7484800912
GSE35957Down-0.6943853497
GSE36640Down-1.2442389806
GSE54402Up0.0699258225
GSE9593Down-0.0056846245
GSE43922Down-1.0649187149
GSE24585Up0.0690858820
GSE37065Down-0.1592000220
GSE28863_A1Down-0.1500610748
GSE28863_A2Down-0.3174453379
GSE28863_A3Up0.0327583821
GSE28863_A4Down-0.0546437524
GSE48662Down-0.6460455653

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-OneDB02185 EXPT01700
Beta-D-GlucoseDB02379 EXPT00685 | EXPT00455 | EXPT01603
Nojirimycine TetrazoleDB02471 EXPT02395
(2s)-Hydroxy(4-Hydroxyphenyl)EthanenitrileDB03430 EXPT01197
PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDEDB08430 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.